privatedna

The tool lets users load raw DNA data files—such as those from 23andMe, MyHeritage, or AncestryDNA—directly in a web browser and computes polygenic risk scores for five psychiatric conditions. All parsing and calculation are performed locally with JavaScript, ensuring that no genetic information is uploaded, stored, or transmitted to any server. The scoring algorithm draws on summary statistics from the Psychiatric Genomics Consortium, translating billions of SNP data into risk estimates that represent a small proportion of overall risk.

Intended for individuals who want to explore genetic risk without sharing their genome, the application emphasizes privacy and transparency. It presents clear consent steps, reminding users that the scores are not medical diagnoses and that environmental factors also influence outcomes. By keeping the entire workflow on the client side, the software provides a private, browser‑based way to view polygenic scores while maintaining the original raw data on the user’s device.